The World Health Organization (WHO) announced on 11 May that mpox, previously known as monkeypox, no longer poses an acute threat to public health across international borders. This declaration comes after mpox was initially classified as a Public Health Event of International Concern (PHEIC) in July 2022 in accordance with the International Health Regulation. Recent months have shown a significant decline in the number of cases reported and no changes in the severity and clinical manifestation of the disease. The WHO stressed that countries should remain vigilant but it is time to shift our focus towards long-term management.